Influence of maternal anemia on placental volume with study of uterine artery doppler

To study the influence of maternal hematocrit [Ht] and hemoglobin [Hb] level on placental volume with study of uterine artery Doppler. In this prospective study 40 pregnant [singleton pregnancy] cases were selected from the outpatient clinic of Alzahra university Hospital. They were divided into two groups the study group [20 cases] were anemic[iron deficiency] and the control group[20cases] were healthy. For each case two scans for the placenta and fetal growth were performed, the first at recruitment and the second 5 weeks later. Placenta volume was measured at each visit using three dimensional ultrasound. The maternal Hb and [Ht] were measured in each visit. It revealed a non statistical significance between maternal hemoglobin, hematocrit and placental volume during the 1[st] visit and 2[nd] visit in anemic group compared to the control group. As regards Doppler study of the uterine artery in the present study it was noted that the pulsatility index and resistance index showed a non significant increase in the anemic group compared to the control group. Maternal iron deficiency anemia can affect placental growth and development. Placental volume increased with mild anemia during the first trimester but has no significant effect of fetal growth. The use of 3D ultrasound is more accurate and efficient safe technique of great value in evaluating placental growth and volume. Also, the study of uterine artery blood flow during the mid second trimester showed a non significant increase of RI and PI with maternal anemia. Further study are needed for the effect of anemia on fetal growth during preconceptional, first, second, third trimester and the outcome of pregnancy

Cardiotocographic studies on fetal condition in cases of pregnancy induced hypertension treated with antihypertensive drugs

Twenty four patients suffering form pregnancy induced hypertension [PIH] attending Al-Azhar Hospital were into three groups each is composed of 8 patients. They received therapeutic doses of labetalol [Trandate], pindolol and clopamide [Viskaldex] and methyl dopa [Aldomet]. The effect of these drugs on maternal blood pressure and fetal condition was studied by cardiography. Viskaldex, has been found to decrease long term variability of fetal heart rate. The other two drugs caused no significant change. Aldomet was found to be less effective in controlling and managing the progress of PIH in severe cases, and the outcome on fetus was less favourable

Fetal biophysical profile scoring versus non-stress test in high risk pregnancy

In 25 cases of high risk pregnancy [6 class A diabetes, 13 pregnancy induced hypertension and 6 anemia with urinary tract infection] the fetus was assessed by nonstress test and the biophysical profile [fetal breathing movements, gross body movement, fetal tone and amniotic fluid volume]. The outcome of pregnancy was assessed by the 5 minutes Apgar score, fetal cord hemoglobin, bilirubin level, birth weight, placental weight and incidence of congenital anomalies. The results were compared with those in 25 control cases [low risk pregnancy] as regards sensitivity of each test, specificity and predictive value

case report of pregnancy with a rare uterine anomaly

An interesting case of conception after surgical removal of rudimentary horn of uterus with ectopic pregnancy is presented. The patient was suffering at the outset of infertility which was treated with clomid to stimulate ovulation. The first pregnancy after treatment was in a rudimentary horn of uterus. The pregnancy was terminated and the rudimentary horn was removed. The patient got pregnant 6 months later

Intrapartum fetal monitor and fetal outcome in cases of pregnancy induced hypertension treated with labetalol pindolol, with clopamide and alphmethyldopa

Twenty-four women with pregnancy induced hypertension [PIH] presenting to Al-Azhar University Hospital in the last trimester of pregnancy were divided into three equal groups. Each group received therapeutic doses of a hypotensive drug [labetalol, pindolol with clopamide and alpha methyldopa]. The effect of these drugs was studied during the intrapartumperiodandthe results were compared with eight normosensitive patients during labor [control group]. No significant change in fetal heart rate [FHR] could be attributed to the drug administrated in case of labetalol alpha methyldopa.As regards pindolol with clopamide, a significant change in long term variability was observed in patients suffering from sever PIH. The pHof fetal blood samples taken from the umbilical cord [UC] did not correlate with maternal pH in patients who received pindolol with clopamide